EN TR
Areas of Care

Head and Neck Cancer

For head and neck cancers, surgery, radiotherapy, chemotherapy, and organ-preserving approaches are coordinated as a personalized plan across our accredited network.

What is head and neck cancer?

Head and neck cancers are the collective name for tumors that form from the uncontrolled growth of cells in the mouth, tongue, larynx, pharynx, salivary glands, and the nose-sinus region.

Most arise from the surface cells lining these areas (squamous cell carcinoma). Early diagnosis protects both survival and functions such as speech and swallowing.

What are the types of head and neck cancer?

They are classified by location:

Oral and tongue cancer

Tumors of the oral cavity and tongue.

Laryngeal cancer

Tumors of the voice box region including the vocal cords.

Pharyngeal cancer

Nasopharyngeal, oropharyngeal, and hypopharyngeal tumors.

Salivary gland cancers

Tumors arising from the salivary glands.

Causes and risk factors

Main risk factors:

  • Smoking and tobacco use
  • Heavy alcohol consumption
  • HPV infection (especially in oropharyngeal cancers)
  • Poor oral hygiene
  • Betel/tobacco chewing habits
  • Occupational dust and chemical exposure

What are the symptoms of head and neck cancer?

They vary by location but include:

  • A non-healing mouth sore or sore throat
  • Persistent hoarseness
  • Difficulty or pain when swallowing
  • A lump felt in the neck
  • White/red patches in the mouth
  • Nasal obstruction, nosebleeds (nasopharynx)

What are the stages of head and neck cancer?

Staging is based on tumor size and spread:

Stage 1

The tumor is small and confined to the site of origin, with no lymph node spread. This is the stage with the highest treatment success.

Stage 2

The tumor has grown or begun to reach nearby lymph nodes.

Stage 3

The cancer has spread to surrounding tissue and regional lymph nodes.

Stage 4

The cancer has spread to distant organs such as lung or bone (metastasis).

HPV-related oropharyngeal cancers respond better to treatment and are assessed separately.

How is head and neck cancer diagnosed?

Diagnosis is made with examination and biopsy:

  • ENT examination and endoscopic evaluation
  • Biopsy of the suspicious area
  • HPV/p16 testing (in oropharyngeal tumors)
  • Pathological examination

Imaging methods in head and neck cancer

For staging and planning:

  • Neck CT and MRI
  • PET-CT (spread and treatment response)
  • Chest CT (distant spread)
  • Ultrasound-guided lymph node assessment

Head and neck cancer treatment methods

Treatment is planned to preserve function:

Surgery

Removing the tumor; robotic/endoscopic and reconstructive techniques.

Radiotherapy

Organ-preserving radiation using advanced techniques such as IMRT.

Chemotherapy

With radiotherapy (chemoradiation) or in advanced disease.

Targeted / immunotherapy

Systemic therapies in suitable advanced or recurrent tumors.

Rehabilitation

Support to preserve speech, swallowing, and nutrition.

Every patient and every tumor is different

No single treatment is right for everyone; the best plan depends on your exact diagnosis, stage, and tumor characteristics. At National Cancer Alliance, we arrange a free second opinion from board-certified oncologists to review your case.

Prognosis and survival rates

Prognosis in head and neck cancers varies by location, stage, and HPV status. Survival is high in early stage and falls in advanced disease; overall 5-year survival is roughly 65–70%.

HPV-related oropharyngeal cancers respond markedly better to treatment and have a better prognosis. Early diagnosis improves both survival and quality of life.

How to reduce head and neck cancer risk

Measures that help lower risk:

  • Quitting tobacco
  • Limiting alcohol
  • Getting the HPV vaccine
  • Paying attention to oral-dental hygiene
  • Regular dental check-ups to detect changes in the mouth early

Frequently asked questions

Is persistent hoarseness important?

Hoarseness lasting more than two-three weeks, especially in smokers, must be evaluated by an ENT physician.

Will treatment affect my speech?

Modern organ-preserving approaches and rehabilitation aim to preserve speech and swallowing.

Is HPV-related cancer different?

Yes. HPV-positive oropharyngeal cancers respond better to treatment and usually have a better course.

Should I get a second opinion?

Function-preserving options vary by center; an independent, multidisciplinary review is very valuable.

Ready for a plan built around you?

Start with a free, no-obligation second opinion from a board-certified oncologist. Have your case reviewed and every option explained clearly.

Get a FREE Second Opinion

This page provides general information about head and neck cancer; it is not a substitute for medical advice, diagnosis, or treatment. All treatments are provided by independent, accredited hospitals and licensed physicians. Your treatment decision should be made by a qualified physician based on your individual situation.